業績紹介

Achivement

2019年業績

• Boda K, Oka S, Tanaka S, Nagata S, Kunihiro M, Kuwai T, Hiraga Y, Furudoi A, Nakadoi K, Okanobu H, Miwata T, Okamoto S and Chayama K.

  Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study.

  Surg Endosc. 2019; In Press.

• Kodama K, Kawaguchi T, Hyogo H, Nakajima T, Ono M, Seike M, Takahashi H, Nozaki Y, Kawanaka M, Tanaka S, Imajo K, Sumida Y, Kamada Y, Fujii H, Seko Y, Takehara T, Itoh Y, Nakajima A, Masaki N, Torimura T, Saibara T, Karino Y, Chayama K and Tokushige K.

  Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis.

  J Gastroenterol Hepatol. 2019; 34: 1626-1632.

• Hayes CN, Imamura M and Chayama K.

  Management of HCV patients in cases of direct-acting antiviral failure.

  Expert Rev Gastroenterol Hepatol. 2019; 13: 839-848.

• Fujino H, Tanaka M, Imamura M, Morio K, Ono A, Nakahara T, Murakami E, Kawaoka T, Takahashi S, Miki D, Tsuge M, Hiramatsu A, Aikata H, Hayes CN and Chayama K.

  Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis.

  BMC Gastroenterol. 2019; 19: 169.

• Mizuno K, Akamatsu S, Sumiyoshi T, Wong JH, Fujita M, Maejima K, Nakano K, Ono A, Aikata H, Ueno M, Hayami S, Yamaue H, Chayama K, Inoue T, Ogawa O, Nakagawa H and Fujimoto A.

  eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA.

  Sci Rep. 2019; 9: 15017.

• Matsumoto K, Oka S, Tanaka S, Tanaka H, Boda K, Yamashita K, Sumimoto K, Ninomiya Y, Arihiro K, Shimamoto F and Chayama K.

  Long-Term Outcomes after Endoscopic Submucosal Dissection for Ulcerative Colitis-Associated Dysplasia.

  Digestion. 2019; 1-11.

• Otani I, Oka S, Aikata H, Iio S, Tsuboi A, Kunihara S, Nagaoki Y, Tanaka S and Chayama K.

  Exacerbation of Portal Hypertensive Enteropathy after Endoscopic Injection Sclerotherapy for Esophageal Varices.

  Digestion. 2019; 1-9.

• Nakamura K, Urabe Y, Oka S, Ito M, Kotachi T, Ninomiya Y, Boda T, Hiyama T, Emi M, Hamai Y, Shiroma N, Tanaka S and Chayama K.

  A case of primary malignant melanoma of the esophagus with a widely expanded surface area.

  Clin J Gastroenterol. 2019; 12: 424-428.

• Yamashita K, Oka S, Tanaka S, Nagata S, Hiraga Y, Kuwai T, Furudoi A, Tamura T, Kunihiro M, Okanobu H, Nakadoi K, Kanao H, Higashiyama M, Kuraoka K, Shimamoto F and Chayama K.

  Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis.

  J Gastroenterol. 2019; 54: 897-906.

• Masuda K, Urabe Y, Ito M, Ono A, Clair Nelson H, Nakamura K, Kotachi T, Boda T, Tanaka S and Chayama K.

  Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy.

  J Gastroenterol. 2019; 54: 907-915.

• Kurihara K, Hanada K, Serikawa M, Ishii Y, Tsuboi T, Kawamura R, Sekitou T, Nakamura S, Mori T, Hirano T, Ikemoto J and Chayama K.

  Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas: A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms.

  Pancreas. 2019; 48: 1312-1320.

• Tamura Y, Kawaoka T, Aikata H, Namba M, Fujii Y, Morio K, Murakami E, Yamauchi M, Hiramatsu A, Nakahara T, Imamura M, Maruhashi T, Kobayashi T, Ohdan H, Kimura T, Nagata Y, Arihiro K and Chayama K.

  Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report.

  Clin J Gastroenterol. 2019; In Press.

• Yorita N, Ito M, Boda T, Kotachi T, Nagasaki N, Abuduwaili M, Hata K, Hiyama Y, Oka S, Yoshihara M, Kitadai Y, Tanaka S and Chayama K.

  Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer.

  J Gastroenterol Hepatol. 2019; 34: 1955-1962.

• Tsuboi A, Oka S, Tanaka S, Iio S, Otani I, Kunihara S and Chayama K.

  The Clinical Usefulness of the PillCam Progress Indicator for Route Selection in Double Balloon Endoscopy.

  Intern Med. 2019; 58: 1375-1381.

• Kishimoto S, Kinoshita Y, Matsumoto T, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, Goto C, Yusoff FM, Nakashima A, Noma K and Higashi Y.

  Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus.

  Am J Hypertens. 2019; In Press.

• Nakano R, Ohira M, Kobayashi T, Ide K, Tahara H, Kuroda S, Shimizu S, Kimura T, Nagata Y, Aikata H, Chayama K and Ohdan H.

  Reply: Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity -matched analysis in a single institution.

  Surgery. 2019; 165: 1054-1057.

• Kishimoto S, Oki K, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, Goto C, Aibara Y, Yusoff FM, Nakashima A, Noma K, Liao JK and Higashi Y.

  Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.

  J Hypertens. 2019; 37: 1083-1095.

• Otani I, Oka S, Tanaka S, Iio S, Tsuboi A, Kunihara S, Hiyama Y and Chayama K.

  Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions.

  Digestion. 2019; 1-8.

• Tsuge M, Uchida T, Walsh K, Ishida Y, Tateno C, Kumar U, Glenn JS, Koh C, Heller T, Uprichard SL, Dahari H and Chayama K.

  Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection.

  Viruses. 2019; 11.

• Hayashi R, Ueno Y, Tanaka S, Wakai M, Kumada J, Fujita A, Nomura M, Oka S, Ito M and Chayama K.

  Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension.

  Intern Med. 2019; 58: 625-631.

• Yamashita K, Oka S, Tanaka S, Nagata S, Kuwai T, Furudoi A, Tamura T, Kunihiro M, Okanobu H, Nakadoi K, Kanao H, Higashiyama M, Arihiro K, Kuraoka K, Shimamoto F and Chayama K.

  Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study.

  Int J Colorectal Dis. 2019; 34: 481-490.

• Osawa M, Imamura M, Teraoka Y, Uchida T, Morio K, Fujino H, Nakahara T, Ono A, Murakami E, Kawaoka T, Miki D, Tsuge M, Hiramatsu A, Aikata H, Hayes CN, Chayama K and Hiroshima Liver Study G.

  Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures.

  J Gastroenterol. 2019; 54: 291-296.

• Hiramatsu A, Aikata H, Uchikawa S, Ohya K, Kodama K, Nishida Y, Daijo K, Osawa M, Teraoka Y, Honda F, Inagaki Y, Morio K, Morio R, Fujino H, Nakahara T, Murakami E, Yamauchi M, Kawaoka T, Miki D, Tsuge M, Imamura M, Tanaka J and Chayama K.

  Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis.

  Hepatol Commun. 2019; 3: 348-355.

• Tanaka K, Takahashi H, Hyogo H, Ono M, Oza N, Kitajima Y, Kawanaka M, Chayama K, Saibara T, Anzai K and Eguchi Y.

  Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease.

  Hepatol Res. 2019; 49: 296-303.

• Kodama K, Kawaoka T, Namba M, Uchikawa S, Ohya K, Morio K, Nakahara T, Murakami E, Yamauchi M, Hiramatsu A, Imamura M, Chayama K and Aikata H.

  Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib.

  Oncology. 2019; 97: 75-81.

• Urabe Y, Kagemoto K, Hayes CN, Nakamura K, Masuda K, Ono A, Tanaka S, Arihiro K and Chayama K.

  Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population.

  Oncotarget. 2019; 10: 4139-4148.

• Maruhashi T, Kajikawa M, Kishimoto S, Matsui S, Hashimoto H, Takaeko Y, Aibara Y, Yusoff FM, Hidaka T, Chayama K, Noma K, Nakashima A, Goto C, Kihara Y and Higashi Y.

  Relationships Between Calcium Channel Blockers and Vascular Function Tests.

  Am J Hypertens. 2019; 32: 640-648.

• Makokha GN, Abe-Chayama H, Chowdhury S, Hayes CN, Tsuge M, Yoshima T, Ishida Y, Zhang Y, Uchida T, Tateno C, Akiyama R and Chayama K.

  Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP.

  Sci Rep. 2019; 9: 8462.

• Kishimoto S, Kinoshita Y, Matsumoto T, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, Goto C, Mohamad Yusoff F, Nakashima A, Noma K and Higashi Y.

  Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus.

  Am J Hypertens. 2019; 32: 695-702.

• Xue R, Chen L, Zhang C, Fujita M, Li R, Yan SM, Ong CK, Liao X, Gao Q, Sasagawa S, Li Y, Wang J, Guo H, Huang QT, Zhong Q, Tan J, Qi L, Gong W, Hong Z, Li M, Zhao J, Peng T, Lu Y, Lim KHT, Boot A, Ono A, Chayama K, Zhang Z, Rozen SG, Teh BT, Wang XW, Nakagawa H, Zeng MS, Bai F and Zhang N.

  Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.

  Cancer Cell. 2019; 35: 932-947 e938.

• Yen CJ, Yang ST, Chen RY, Huang W, Chayama K, Lee MH, Yang SJ, Lai HS, Yen HY, Hsiao YW, Wang JM, Lin YJ and Hung LY.

  Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis.

  J Biomed Sci. 2019; 26: 44.

• Hamdane N, Juhling F, Crouchet E, El Saghire H, Thumann C, Oudot MA, Bandiera S, Saviano A, Ponsolles C, Roca Suarez AA, Li S, Fujiwara N, Ono A, Davidson I, Bardeesy N, Schmidl C, Bock C, Schuster C, Lupberger J, Habersetzer F, Doffoel M, Piardi T, Sommacale D, Imamura M, Uchida T, Ohdan H, Aikata H, Chayama K, Boldanova T, Pessaux P, Fuchs BC, Hoshida Y, Zeisel MB, Duong FHT and Baumert TF.

  HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

  Gastroenterology. 2019; 156: 2313-2329 e2317.

• Yano T, Ohira M, Sakamoto R, Narisada A, Shimizu S, Tahara H, Ide K, Kobayashi T, Imamura M, Machino A, Yamawaki S, Chayama K and Ohdan H.

  Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation.

  Transplant Proc. 2019; 51: 1934-1938.

• Takaeko Y, Matsui S, Kajikawa M, Maruhashi T, Kishimoto S, Hashimoto H, Kihara Y, Hida E, Chayama K, Goto C, Aibara Y, Yusoff FM, Noma K, Nakashima A and Higashi Y.

  Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men.

  J Clin Lipidol. 2019; 13: 664-672 e661.

• Kajikawa M, Maruhashi T, Hidaka T, Matsui S, Hashimoto H, Takaeko Y, Nakano Y, Kurisu S, Kihara Y, Yusoff FM, Kishimoto S, Chayama K, Goto C, Noma K, Nakashima A, Hiro T, Hirayama A, Shiina K, Tomiyama H, Yagi S, Amano R, Yamada H, Sata M and Higashi Y.

  Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study.

  Sci Rep. 2019; 9: 10206.

• Tsushima K, Tsuge M, Hiraga N, Uchida T, Murakami E, Makokha GN, Kurihara M, Nomura M, Hiyama Y, Fujino H, Ono A, Nakahara T, Yamauchi M, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Aikata H, Hayes CN and Chayama K.

  Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.

  J Gastroenterol. 2019; 54: 650-659.

• Osawa M, Uchida T, Imamura M, Teraoka Y, Fujino H, Nakahara T, Ono A, Murakami E, Kawaoka T, Miki D, Tsuge M, Hiramatsu A, Abe-Chayama H, Hayes CN, Makokha GN, Aikata H, Ishida Y, Tateno C, Miyayama Y, Hijikata M and Chayama K.

  Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice.

  J Gen Virol. 2019; 100: 1123-1131.

• Tatsukawa Y, Tsuge M, Kawakami Y, Hiyama Y, Murakami E, Kurihara M, Nomura M, Tsushima K, Uchida T, Nakahara T, Miki D, Kawaoka T, Abe-Chayama H, Imamura M, Aikata H, Ochi H, Hayes CN, Kawakami H and Chayama K.

  Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study.

  Antivir Ther. 2019; 23: 709.

• Tanaka H, Oka S, Tanaka S, Matsumoto K, Boda K, Yamashita K, Hirano D, Sumimoto K, Tamaru Y, Ninomiya Y, Hayashi N and Chayama K.

  Dual Red Imaging Maintains Clear Visibility During Colorectal Endoscopic Submucosal Dissection.

  Dig Dis Sci. 2019; 64: 224-231.

• Takehara T, Sakamoto N, Nishiguchi S, Ikeda F, Tatsumi T, Ueno Y, Yatsuhashi H, Takikawa Y, Kanda T, Sakamoto M, Tamori A, Mita E, Chayama K, Zhang G, De-Oertel S, Dvory-Sobol H, Matsuda T, Stamm LM, Brainard DM, Tanaka Y and Kurosaki M.

  Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial.

  J Gastroenterol. 2019; 54: 87-95.

• Bazerbachi F, Haffar S, Wang Z, Cabezas J, Arias-Loste MT, Crespo J, Darwish-Murad S, Ikram MA, Olynyk JK, Gan E, Petta S, Berzuini A, Prati D, de Ledinghen V, Wong VW, Del Poggio P, Chavez-Tapia NC, Chen YP, Cheng PN, Yuen MF, Das K, Chowdhury A, Caballeria L, Fabrellas N, Gines P, Kumar M, Sarin SK, Conti F, Andreone P, Sirli R, Cortez-Pinto H, Carvalhana S, Sugihara T, Kim SU, Parikh P, Chayama K, Corpechot C, Kim KM, Papatheodoridis G, Alsebaey A, Kamath PS, Murad MH and Watt KD.

  Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals.

  Clin Gastroenterol Hepatol. 2019; 17: 54-64 e51.

• Tanaka H, Oka S, Tanaka S, Inagaki K, Okamoto Y, Matsumoto K, Boda K, Yamashita K, Sumimoto K, Ninomiya Y, Hayashi N and Chayama K.

  The utility of a novel colonoscope with retroflexion for colorectal endoscopic submucosal dissection.

  Endosc Int Open. 2019; 7: E130-E137.

• Ishii Y, Serikawa M, Sasaki T, Fujimoto Y, Yamaguchi A, Ogawa T, Noma B, Okazaki A, Yukutake M, Ishigaki T and Chayama K.

  Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis.

  Scand J Gastroenterol. 2019; 54 259-264.

• Miyayama Y, Lee H, Song H, Abe-Chayama H, Miki D, Imamura M, Chayama K and Hijikata M.

  Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs.

  Microbiol Immunol. 2019; In Press.

• Ohya K, Kawaoka T, Imamura M, Morio K, Nakahara T, Murakami E, Yamauchi M, Hiramatsu A, Tsuge M, Aikata H and Chayama K.

  Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection.

  Intern Med. 2019; In Press.

• Hata K, Ito M, Boda T, Kotachi T, Kiso M, Hiyama Y, Kuroki K, Yorita N, Nagasaki N, Abduwaili M, Tanaka S and Chayama K.

  The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study.

  Intern Med. 2019; In Press.

• Ohya K, Kawaoka T, Namba M, Uchikawa S, Kodama K, Morio K, Nakahara T, Murakami E, Hiramatsu A, Tsuge M, Yamauchi M, Imamura M, Chayama K and Aikata H.

  Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy.

  Sci Rep. 2019; 9: 12101.

• Namba M, Kawaoka T, Aikata H, Kodama K, Uchikawa S, Ohya K, Morio K, Fujino H, Nakahara T, Murakami E, Yamauchi M, Tsuge M, Hiramatsu A, Imamura M, Baba Y, Awai K and Chayama K.

  Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt.

  Clin J Gastroenterol. 2019; 12: 341-346.

• Fujii H, Imajo K, Yoneda M, Nakahara T, Hyogo H, Takahashi H, Hara T, Tanaka S, Sumida Y, Eguchi Y, Chayama K, Nakajima A, Nishimoto N, Kawada N and Japan Study Group of Nonalcoholic Fatty Liver D.

  HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease.

  J Gastroenterol Hepatol. 2019; 34: 1390-1395.

• Naganuma A, Chayama K, Notsumata K, Gane E, Foster GR, Wyles D, Kwo P, Crown E, Bhagat A, Mensa FJ, Otani T, Larsen L, Burroughs M and Kumada H.

  Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection.

  J Gastroenterol. 2019; 54: 752-761.

• Takaguchi K, Toyoda H, Tsutsui A, Suzuki Y, Nakamuta M, Imamura M, Senoh T, Nagano T, Tada T, Tachi Y, Hiraoka A, Michitaka K, Shibata H, Joko K, Okubo H, Tsuji K, Takaki S, Watanabe T, Ogawa C, Chayama K, Kumada T, Kudo M and Kumada H.

  Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan.

  J Gastroenterol. 2019; 54: 742-751.

• Maruhashi T, Kinoshita Y, Kajikawa M, Kishimoto S, Matsui S, Hashimoto H, Takaeko Y, Aibara Y, Yusoff FM, Hidaka T, Chayama K, Noma K, Nakashima A, Goto C, Takahashi M, Kihara Y, Higashi Y and Hiroshima NRG.

  Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment.

  Hypertens Res. 2019; 42: 1175-1185.

• Takigawa H, Masaki S, Naito T, Yuge R, Urabe Y, Tanaka S, Sentani K, Matsuo T, Matsuo K, Chayama K and Kitadai Y.

  Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma.

  Cancer Med. 2019; 8: 4370-4379.

• Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Juhling F, Oudot MA, Virzi A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N and Baumert TF.

  Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development.

  Gastroenterology. 2019; 157: 537-551 e539.

• Kajikawa M, Maruhashi T, Kishimoto S, Matsui S, Hashimoto H, Takaeko Y, Yusoff FM, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Tomiyama H, Takase B, Kohro T, Suzuki T, Ishizu T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Watanabe K, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Maemura K, Ohya Y, Furukawa T, Ito H, Ikeda H, Yamashina A and Higashi Y.

  Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease- Post Hoc Analysis of the FMD-J Study A.

  Circ J. 2019; 83: 1064-1071.

• Nagaoki Y, Imamura M, Nishida Y, Daijo K, Teraoka Y, Honda F, Nakamura Y, Morio K, Fujino H, Nakahara T, Kawaoka T, Tsuge M, Hiramatsu A, Kawakami Y, Miki D, Hiyama Y, Ochi H, Chayama K and Aikata H.

  The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma: Comparison with interferon-based therapy.

  J Med Virol. 2019; 91: 650-658.

• Tateishi R, Uchino K, Fujiwara N, Takehara T, Okanoue T, Seike M, Yoshiji H, Yatsuhashi H, Shimizu M, Torimura T, Moriyama M, Sakaida I, Okada H, Chiba T, Chuma M, Nakao K, Isomoto H, Sasaki Y, Kaneko S, Masaki T, Chayama K and Koike K.

  A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update.

  J Gastroenterol. 2019; 54: 367-376.

• Urabe Y, Kagemoto K, Nakamura K, Mizumoto T, Sanomura Y, Oka S, Ochi H, Tanaka S and Chayama K.

  Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma.

  Esophagus. 2019; 16: 141-146.

• Kajikawa M, Maruhashi T, Hidaka T, Nakano Y, Kurisu S, Matsumoto T, Iwamoto Y, Kishimoto S, Matsui S, Aibara Y, Yusoff FM, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Watanabe T, Tone H, Hibi M, Osaki N, Katsuragi Y and Higashi Y.

  Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension.

  Eur J Nutr. 2019; 58: 989-996.

• Hata K, Ito M, Boda T, Kotachi T, Kiso M, Masuda K, Kurihara M, Kuroki K, Yorita N, Nagasaki N, Abduwali M, Tanaka S and Chayama K.

  Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey.

  Digestion. 2019; 99: 59-65.

• Hirano D, Urabe Y, Tanaka S, Nakamura K, Ninomiya Y, Yuge R, Hayashi R, Oka S, Kitadai Y, Shimamoto F, Arihiro K and Chayama K.

  Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes.

  PLoS One. 2019; 14: e0211477.

• Takeuchi F, Ikeda S, Tsukamoto Y, Iwasawa Y, Qihao C, Otakaki Y, Ryota O, Yao WL, Narita R, Makoto H, Watashi K, Wakita T, Takeuchi K, Chayama K, Kogure A, Kato H and Fujita T.

  Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.

  PLoS One. 2019; 14: e0212233.

• Amioka M, Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, Motoda C, Matsumura H, Tomomori S, Hironobe N, Okubo Y, Okamura S, Chayama K and Kihara Y.

  Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation.

  PLoS One. 2019; 14: e0213208.

• Tsuboi A, Oka S, Tanaka S, Iio S, Otani I, Kunihara S, Hayashi R and Chayama K.

  Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?

  Gastroenterol Res Pract. 2019; 2019: 1262595.

• Hayes CN, Zhang P and Chayama K.

  The Role of Lipids in Hepatocellular Carcinoma.

  Tirnitz-Parker JEE, editor. 2019. In Press.

• Tanaka H, Oka S, Tanaka S, Inagaki K, Okamoto Y, Matsumoto K, Boda K, Yamashita K, Sumimoto K, Ninomiya Y and Chayama K.

  Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?

  J Anus Rectum Colon. 2019; 3: 128-135.

• Cui Y, Moriyama M, Chayama K, Liu Y, Ya C, Muzembo BA and Rahman MM.

  Efficacy of a self-management program in patients with chronic viral hepatitis in China.

  BMC Nurs. 2019; 18: 44.

• Iio S, Oka S, Tanaka S, Tsuboi A, Otani I, Kunihara S and Chayama K.

  Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding.

  Gastroenterol Res Pract. 2019; 2019: 5496242.